Triple flexion brain injury. (24636925) Apr 20, 2016 · In patients with impaired arousal, sedating and paralyzing agents must be interrupted and verbal and motor responses including those elicited by noxious stimulation noted. Here, we report a brain-dead patient with finger flexion in the upper extremities with noxious stimulation. 4 Here, we reported another dramatic These include subtle ocular micro-tremors to obvious limb reflexes (such as triple flexion in the lower extremities) or of the torso (the “Lazarus” sign) [5]. The clinical signs of this phenomenon include Babinski's response, triple flexion of leg and gross flexor, or sometimes extensor spasm which may be produced by simple and non-noxious cutaneous stimuli. It is a spinal reflex that occurs without voluntary control and can be present in conditions like brain injuries or spinal cord dysfunction. In summary, spontaneous or reflex movements are frequent in brain death. Triple Flex Reflex is s spinal cord reflex. Introduction Predicting recovery of consciousness and functional capacity in patients with severe traumatic brain injury (TBI) is a common challenge that confronts clinicians in civilian and military intensive care units [1]. 3 Lazarus sign is a rare complex movement consisting of bilateral arm flexion to chest, shoulder adduction, and hand crossing, which can be seen in 1. These movements may be more common than reported and do not preclude the diagnosis of BD. The most concerning mimics of brain death are missed alternative diagnoses (e. Mar 14, 2016 · Abnormal movements are frequently encountered in patients with brain injury hospitalized in intensive care units (ICUs), yet characterization of these movements and their underlying pathophysiology is difficult due to the comatose or uncooperative state of the patient. (24636925) Mar 3, 2025 · What is Triple Flexion? Triple flexion is an involuntary reflex movement involving simultaneous flexion of the hip, knee, and ankle in response to stimuli, often seen in neurological assessments. Jan 11, 2000 · The most common movement was finger jerks. Triple flexion is also suggested if the patient responds exactly the same way, regardless of where their foot is stimulated (e. Jan 14, 2026 · Extremity flexion without grimacing in the lower extremity may be seen in the presence of brain death, due to a spinal reflex known as triple flexion. In addition, the available diagnostic approaches are largely derived from outpatients with neurodegenerative or developmental Aug 28, 2017 · Spinal reflexes may produce strange movements among brain dead patients, often causing confusion. Dec 9, 2013 · This movement is a reflex, it is not purposeful. ) Pearl: We cannot change the degree of primary injury from the hypoxic ischemic brain injury (HIBI), but we can prevent secondary neurologic injuries. 5% of brain-dead patients. Dec 29, 2021 · The next day, he is comatose, with no brainstem reflexes and no movement in his arms or legs other than bilateral triple-flexion signs in response to noxious stimulation. . Jan 14, 2026 · Extremity flexion without grimacing in the lower extremity may be seen in the presence of brain death, due to a spinal reflex known as triple flexion. , dorsum vs. Patients may exhibit this reflex when brain dead. Clinical Significance Recognizing triple flexion posturing is important in a medical context because its presence often indicates significant neurological impairment. Movements in the upper extremities have largely been under-recognized. sole). Radionuclide flow scan may be used in confusing situations. It serves as a sign of severe central nervous system injury, particularly damage to the spinal cord or brain pathways controlling motor function. intoxication, C-spine injury), because these may be treatable. g. Jul 7, 2012 · The most common spinal response is triple flexion response (flexion in foot, knee, and hip) which may have variations such as undulating toe sign or a Babinski sign. In our study, the most common were the undulating toe reflex and the triple flexion response. The diagnosis of brain death has implications for family members, patients on transplant waiting lists, and health care providers. Plantar flexion, myoclonus, triple flexion reflex, and pronator extension reflex are the common spinal reflexes in brain death. Role of Spinal Inhibitory Mechanisms in Spasticity Nov 3, 2022 · There is abnormal flexure posturing in the uppers and triple flexion in the lowers. Undulating toe flexion sign, triple flexion response, Lazarus sign, pronation–extension reflex, and facial myokymia also were seen. Purposeful movements must be distinguished from spinal cord-mediated triple flexion reflex (hip flexion, knee flexion, and dorsiflexion of the foot) and decorticate posturing. Research Snapshot: Neurology 750: Triple Flexion-Like Movements in Brain Death Determination Babiker, Ahmed 1; Patel, Dhiren 1; Shah, Manan 1; Switzer, Jeffrey 2; Garcia, Klepper Alfredo 1 Author Information These include subtle ocular micro-tremors to obvious limb reflexes (such as triple flexion in the lower extremities) or of the torso (the “Lazarus” sign) [5]. These movements were observed mainly within the first 24 hours after declaration of brain death and consisted of spontaneous jerks of the fingers, undulating toe flexion, triple flexion, unilateral facial myokymia, “Lazarus sign,” upper limb pronation/extension reflex, and flexor plantar response. Flexion withdrawal, the red nucleus is responsible for the upper arm movements and the leg movements are a due to activity in the lateral corticospinal tract of the spinal cord.
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